Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
60-35-5	Acetamide	100	200-473-5

Section 3 - Hazards Identification

Appearance: white solid.
Caution! May cause eye and skin irritation. May cause respiratory tract irritation. May cause cancer based on animal studies. Potential cancer hazard. May cause liver damage. Hygroscopic (absorbs moisture from the air).
Target Organs: Liver.


Potential Health Effects
Eye: May cause eye irritation.
Skin: Causes mild skin irritation.
Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. May cause liver damage.
Inhalation: May cause respiratory tract irritation. May cause liver damage.
Chronic: Possible cancer hazard based on tests with laboratory animals. May cause cancer according to animal studies. Chronic exposure may cause liver damage.

Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Dusts may be combustible when exposed to heat, flame, or oxidizing agents. Dust can be an explosion hazard when exposed to heat or flame.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water or foam may cause frothing. Use water spray to cool fire-exposed containers.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 1; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Avoid generating dusty conditions. Provide ventilation. Clean up residual material by washing area with a 2-5% solution of soda ash.

Section 7 - Handling and Storage

Handling: Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Use with adequate ventilation.
Storage: Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
Acetamide	none listed	none listed	none listed

OSHA Vacated PELs: Acetamide: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: white
Odor: mousy like odor
pH: Not available.
Vapor Pressure: Negligible.
Vapor Density: ~2
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: 221 deg C
Freezing/Melting Point:80 deg C
Decomposition Temperature:Not available.
Solubility: 200% in water.
Specific Gravity/Density:1.16
Molecular Formula:C2H5NO
Molecular Weight:59.07

Section 10 - Stability and Reactivity

Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid: Dust generation, moisture, excess heat.
Incompatibilities with Other Materials: Strong oxidizers, metals, halogenated materials.
Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#:      
CAS# 60-35-5: AB4025000
LD50/LC50:
CAS# 60-35-5:
     Oral, mouse: LD50 = 12900 mg/kg;
     Oral, rat: LD50 = 7 gm/kg;
.

Carcinogenicity:
CAS# 60-35-5:

• ACGIH: Not listed.
  
• California: carcinogen, initial date 1/1/90
  
• NTP: Not listed.
  
• IARC: Group 2B carcinogen